Stimulation of pro-apoptotic
molecules or inhibition of apoptotic
factors are dependent on the cell type and the form of insult.
Results: The results of this study showed that PTZ-induced neuronal cell death by activation of pro apoptotic
proteins caspase-3 and 9 whereas the exposure of metformin showed its protective effect against neuronal loss in HCN-2 cell line.
There was no significant correlation between peak apoptotic
activity levels at 72 hours of reperfusion and peak creatine kinase myocardial band (r=0.
Caspase 3 is an "effector" marker; associated with initiation of apoptotic
The hematoxylin-eosin stained slides were screened under 40X objective and 10X eyepiece, but the final count of apoptotic
cells were carried out under high magnification (Oil immersion x 100 lens).
cells were detected by fluorescence-activated cell sorting (FACS) with the FITC Annexin V Apoptosis Detection Kit I (eBiosciences, San Diego, CA, USA).
Natural products are structurally diverse compounds with anti tumor activity and low side effects that improve human health and have pivotal function to eliminate tumor cells by modulation of apoptotic
In the present study, we examined the apoptotic
effect of Saxi A in two breast cancer cell lines, MCF-7 and MDA-MB-231, and the significance of ER[alpha] status on Saxi A-induced cytotoxicity.
As has been highlighted earlier, while the extrinsic apoptotic
pathway plays a role in villous atrophy in patients with celiac disease, studies on the intrinsic and common apoptotic
pathways in patients with celiac disease are sparse.
Hotchkiss et al showed that both the extrinsic and intrinsic apoptotic
pathways are important in the pathogenesis of sepsis (12) and that there may be communications and interactions between the two apoptotic
pathways mediated by the truncated form of BH3, produced by caspase-8 mediated BID cleavage.
The molecular signaling cascade including phospho-Akt (ser-473) and HIF-1alpha that lead to the activation or suppression of apoptotic
pathway also showed a significant protective role in the treatment group.
In addition, increased apoptotic
process continues during hyperthermia (5,6).
com)-- Bioo Scientific announced today that it has launched the D-Pop[TM] Kit to facilitate the analysis of DNA from apoptotic
We determined the cell proliferation rate, apoptotic
rate, and p53 protein expression level in the mammary gland to understand the cell turnover rate during the dry period under high temperature conditions.
Natural compounds and their role in apoptotic
cell signaling pathways.