Drug treatment for patients with diarrheal symptoms usually starts with either an anti-spasmodic or an antidiarrheal
agent; in some cases, the two classes are used together.
Watch especially for decreased frequency of stools when anticholinergics, antidepressants, anti-psychotics, antidiarrheal
, diuretics, NSAIDs, iron, calcium, zinc or bismuth salts, salts, colestipol, cholestyramine, Kayexalate or cold and sinus medications are started.
Doctors commonly recommend over-the-counter medications such as laxatives, antidiarrheals
, and bulking agents for IBS.
Table 33: Global Leading Drug Value Sales by Category for Treating Irritable Bowel Syndrome: Annual Market Estimates for 2003 through 2008 in Millions of US$ for Laxatives, Antidiarrheals
, and Antidepressants 120
Most patients are still treated with older drugs that offer limited efficacy such as fiber, bulk laxatives, and antidiarrheals
None reported being very satisfied and 38 percent are dissatisfied with treatments that included laxatives, dietary changes, fiber supplements, acid reducers, stool softeners, antidiarrheals
, gas relief medications and other medications.
Patients may require antiemetics, antidiarrheals
and fluid and electrolyte replacement (to prevent dehydration).
The study analyzes six segments: traditional antacids, H2 receptor antagonists, proton pump inhibitors, laxatives, antidiarrheals
, and stomach remedies.
The first tier of the expansion involves adding hundreds of drugs from classifications of medications such as specific vaccines, antidepressants, analgesics, migraine agents, antiemetics and antidiarrheals
Quality of life, lifestyle changes, and use of antidiarrheals
or other medications for symptom relief were also assessed.
Irritable Bowel Syndrome Therapeutics Markets, part of the Pharmaceuticals Monitor Service subscription, examines the following product segments: anticholinergics, antidiarrheals
, laxatives, antidepressants, and 5-HT modulators.