This work adds to the evidence that anticholinergics
should be avoided in a wide-range of populations, when possible, said one of the researchers Ian Maidment, senior lecturer in clinical pharmacy at Aston University in Birmingham, England.
Scientists tracked the health of 3434 men and women aged 65 and over for about seven years while monitoring their use of anticholinergic
Experts tracked the health of 3,434 over-65s and their use of anticholinergic
drugs, like antihistamine diphenhydramine, for seven years.
medication was initiated in patients whose symptoms did not improve after 6 months of strict bladder retraining or whose bladder had less than 65% of its expected capacity based on age (30 + [age in years x 30] mL)[sup.
The majority of children with neurogenic bladder (70-90%) are effectively managed with oral anticholinergics
and clean intermittent catheterisation, avoiding the need for surgical intervention, e.
Cost analyses assumed that Botox patients incurred no additional costs between months 6 and 9 while those on anticholinergics
incurred an additional 3 months of medication costs.
bronchodilators such as SpirivaA (tiotropium) are established as base-line maintenance therapy in the treatment of COPD.
The proportion of women with complete resolution of urgency incontinence was 13 percent with anticholinergics
and 27 percent with onabotulinum toxin-A.
The majority of a Food and Drug Administration advisory panel recommended that aclidinium bromide, an inhaled long-acting anticholinergic
bronchodilator, should be approved as a treatment for chronic obstructive pulmonary disease, with a postmarketing study that evaluates the cardiovascular safety of the drug.
However, evidence is lacking for long-acting anticholinergics
such as tiotropium bromide producing additional benefits to beta-2 agonists in long-term therapy.
A related presentation from the American Geriatric Society reported that older adults using anticholinergics
demonstrated slower walking speed and were more likely to need help with activities of daily living compared with people who did not take the drugs.
4) Overall it appears that anticholinergics
provide less bronchodilatation than the SABA.
Treatment for ptyalism was not necessary in this parrot; however, treatment in other species generally involves surgical resection or medical treatment with anticholinergics
or botulinum toxin A injections.
In healthy volunteers and the elderly, several single or brief multidose studies have most consistently demonstrated that anticholinergics
decrease DM and NDM.
To accomplish this, anticholinergics
(oxybutinin chloride or tolterodine) may be prescribed.