cytotoxicity

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Related to Antibody-dependent cell-mediated cytotoxicity: antibody-dependent cell-mediated cytotoxicity (ADCC)
  • noun

Words related to cytotoxicity

the degree to which something is toxic to living cells

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References in periodicals archive ?
further enhance the therapeutic properties of SIMPLE Antibody(TM) leads in terms of their residence time in the body, their ability to clear disease targets or pathogenic antibodies and their cell killing potency through Antibody-Dependent Cell-mediated Cytotoxicity (ADCC), respectively.
Of particular note, it has been found to have potent antibody-dependent cell-mediated cytotoxicity (ADCC), complement-dependent cytotoxicity (CDC), and apoptotic activity (achievement of programmed cell death).
PEGPH20, by removing HA from the cancer cell surface, potentially allows greater contact of NK cells to tumor cells, a key process involved in antibody-dependent cell-mediated cytotoxicity of cancer cells.
TG20 has enhanced antibody-dependent cell-mediated cytotoxicity (ADCC), a key feature useful in the treatment of cancer and auto-immune diseases, and it has been shown to have 10-fold enhanced ADCC when compared side by side with rituximab in assays performed with B-cell chronic lymphocytic leukemia, or B-CLL, patient cancer cell isolates.
MacroGenics has optimized the Fc region of margetuximab to increase cancer cell killing via Antibody-Dependent Cell-mediated Cytotoxicity (ADCC).
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