The leaves of Annona reticulata were collected from Dhaka district, Bangladesh during January, 2011.
Groups 8-11 were administered methanolic extract of Annona reticulata leaves at doses of 50, 100, 200 and 400 mg per kg body weight, respectively.
Methanolic extract of leaves of Annona reticulata, when administered at doses of 50, 100, 200 and 400 mg extract per kg body weight reduced the number of writhings, respectively, by 47.
Therefore any agent (like the extracts of leaves of Annona reticulata and Carissa carandas) that lowers the number of abdominal constrictions will demonstrate analgesia possibly by inhibition of prostaglandin synthesis.
The leaves of Annona reticulata and Carissa carandas were collected from Uttara in Dhaka city in January 2011.
Glucose tolerance property of methanol extract of Annona reticulata and Carissa carandas leaves was determined as per the procedure previously described by Joy and Kuttan (1999) with minor modifications.
As also shown in Table 1, the crude methanol extract of Annona reticulata leaves exhibited strong antihyperglycemic activity when administered to glucose-loaded mice.
Table 1: Effect of methanol extract of Carissa carandas and Annona reticulata leaves on serum glucose level in hyperglycemic mice following 120 minutes of glucose loading.