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Key Words: Leukemia, Megaloblastic Anemia, Aplastic Anemia
It is not a disease entity but a triad of findings that may result from a number of disease processes, the important ones of which are myelodysplasia, leukemia, megaloblastic anemia, aplastic anemia, infiltration of bone morrow due to lymphoma and solid tumors.
3 Most of the causes of pancytopenia present with normal RBC indices,4 but causes like megaloblastic anemia, aplastic anemia, myelodysplastic syndrome and paroxysmal nocturnal hemoglobinuria present with high MCV.
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