The Anacyclus pyrethrum root extract was prepared as previously described (Boonen et al.
Pellitorine was isolated and purified from the Anacyclus pyrethrum extract by means of semi-preparative HPLC as follows.
Dose solutions of the Anacyclus pyrethrum extract and the purified pellitorine were prepared in 30:70 [H.
Human skin was used and the analyses were done in fourfold for the purified pellitorine and in sextuplicate for the Anacyclus pyrethrum extract, using a randomised blocked design.
The purity of the Anacyclus pyrethrum extract and the purified pellitorine was determined by HPLC-UV.
4 for both the purified pellitorine and pellitorine in the Anacyclus pyrethrum extract.
The steady-state permeability coefficient of pellitorine in the Anacyclus pyrethrum extract was thus significantly higher than the [K.
Our findings demonstrate for the first time that the plant diene N-alkylamide pellitorine from an Anacyclus pyrethrum extract permeates the skin.
Anacyclus pyrethrum therefore appears to be a plant rich in secondary metabolites.
Centre for Mediterranean Cooperation, International Union for Conservation of Nature and Natural Resources: Anacyclus pyrethrum L.
Immunologically Active Polysaccharides Isolated from Anacyclus pyrethrum.
In vitro antibacterial activity of the methanolic and aqueous extracts of Anacyclus pyrethrum used in moroccan traditional medicine.
Determination of Antibacterial Activity of Anacyclus Pyrethrum Extract against Some of the Oral Bacteria: An In Vitro Study.
Antidiabetic Effect of Anacyclus pyrethrum DC in Alloxan Induced Diabetic Rats.
Valorisation d'une plante medicinale a activite antidiabetique de la region de Tlemcen : Anacyclus pyrethrum L.