We are aware of one case report in the literature describing a 47-year-old woman who took an overdose of baclofen, amitryptiline
and alcohol and who developed features of diabetes insipidus: polyuria, low serum osmolality and high plasma osmolality which responded to desmopressin (5).
Drugs that triggered Torsades de Pointes Antibiotic agents Anti-arrhythmics Psychotropic agents Erythromycin (n=4) Sotalol (n=3) Amitryptiline
(n=1) Roxithromycin (n=2) Ibutilide (n=1) Haloperidol (n=1) Gatifloxacin (n=2) Quinidine (n=1) Fluoxetine (n=1) Clarithromycin (n=1) Amiodarone (n=1) Risperidone (n=1) Levofloxacin (n=1) Antibiotic agents Anti-histamines Erythromycin (n=4) Astemisol (n=2) Roxithromycin (n=2) Terfanidine (n=1) Gatifloxacin (n=2) Clarithromycin (n=1) Levofloxacin (n=1)
Paul Pitts took an overdose of amitryptiline
after he received "bad news" from his girlfriend while serving a seven-year sentence at Stafford Jail.
(Elavil), clonazepam (Klonopin), diazepam (Valium), or applications of heat and cold are also useful.
True (A) or false (B)--fill in only block A or B: Amitryptiline
remains a first-line therapy of choice in DPN.