EVALUATING THE INTERACTIONS BETWEEN AMINOACYL-tRNA
SYNTHETASES AND ELONGATION FACTOR TU IN PROTEIN SYNTHESIS
This bias exists among the 61 amino acid codons found in mRNA molecules, and the levels of aminoacyl-tRNAs
seem to correlate with the frequency of codon usage [3,4].
Rodriguez performed many laborious experiments in which she removed portions of the aminoacyl-tRNA
synthetase that interact with the anticodon stem of the transfer RNA, far from the part of the enzyme that binds the amino acid.
24)] Miscellaneous Aminoacyl-tRNA
synthetase autoantibodies [Park et al.
Utilizing "Omics" to Unlock Aminoacyl-tRNA
Synthetase Therapeutic Potential.
In the GTP-bound form of the molecule, EF-Tu binds tightly to aminoacyl-tRNA
, forming a ternary complex that interacts with the ribosomal acceptor site.
Antibacterial activity will be achieved through inhibition of essential aminoacyl-tRNA
Stimulatory effect of genistein and daidzein on protein synthesis in osteoblastic MC3T3-E1 cells: activation of aminoacyl-tRNA
Recent study results have suggested that Hcy-induced vascular damage could be a result of Hcy-thiolactone (HcyT), an Hcy-reactive product formed in several cell types as a result of editing reactions of some aminoacyl-tRNA
synthetase (5, 6).
11:00 Size Identification of Aminoacyl-tRNA
Synthetases from Plants
In these 36 reports, contributors describe their most recent research in aminoacyl-tRNA
synthetases, the point in gene expression in which the genetic code is first defined.
HARS is part of the ancient gene family of aminoacyl-tRNA
synthetases (aaRS), which has been known for decades to function intracellularly in protein synthesis.
The existence of a complex of aminoacyl-tRNA
synthetases in plants is still in question.
Translational accuracy of aminoacyl-tRNA
synthetases: implications for atherosclerosis.
While the anti-fungal effect of the LeuRS protein inhibition by boron-containing compounds has been established by the clinical results seen for AN2690, other proteins from the same family, known as aminoacyl-tRNA
synthetases, are well-validated targets for antibiotic drug development.