Maurice Van Steensel of Maastricht (the Netherlands) University commented that a truly double-blind study is impossible with afamelanotide because the alpha-melanocyte-stimulating hormone
analogue causes tanning.
Cutaneous immunomodulation and coordination of skin stress responses by alpha-melanocyte-stimulating hormone
The study, titled, "Autocrine inhibitory influences of alpha-melanocyte-stimulating hormone
in malignant pleural mesothelioma," showed that activation of express melanocortin 1 receptor (MC1R) by selective peptides or peptidomimetics might provide a novel strategy to reduce mesothelioma cell proliferation by taking advantage of an endogenous inhibitory circuit based on alpha-Melanocyte-Stimulating Hormone
(alpha-MSH), and its receptor MC1R.
Zengen's peptides have broad applications as anti-inflammatory and anti-infective prescription pharmaceuticals and are based on the larger melanocortin peptide, alpha-Melanocyte-Stimulating Hormone
has announced that its researchers have discovered that supplementation with alpha-Melanocyte-Stimulating Hormone
(alpha-MSH), a naturally occurring molecule that modulates inflammatory and immune responses, may be beneficial in patients with brain injury.