Effect of acarbose, an alpha-glucosidase inhibitor
, on serum lipoprotein lipase mass levels and common carotid artery intima-media thickness in type 2 diabetes mellitus treated by sulfonylurea.
The alpha-glucosidase inhibitor
l-blocks human immunodeficiency virus envelope glycopro-tein-mediated membrane fusion at the CXCR4 binding step.
Highlights of the presentation include: - Recent HCV Phase II non-responder study results using the Company's oral alpha-glucosidase inhibitor
, celgosivir (MX-3253), in combination with pegylated interferon and ribavirin - Omigard(TM) for the prevention of local catheter-related site infections in an international (US & Europe) confirmatory Phase III study About MIGENIX
TSX: MGI, OTC: MGIFF), a clinical-stage developer of drugs for infectious diseases, has received new top-line results confirming the previously announced clinical results (November 6, 2006) indicating evidence of clinical benefit, safety and tolerability in a Phase II study using the oral alpha-glucosidase inhibitor
, celgosivir (MX-3253), in combination with pegylated interferon and ribavirin.
And these treatment categories: - Thiazolidinediones - Alpha-glucosidase inhibitors
- Meglitinides - Sodium-glucose co-transporter-2 inhibitors (SGLT2) - Other agents (grouped).
Antidiabetics Market Analysis By Product (Insulin, Biguanides, Thiazolodinediones, GLP-agonists, Sulphonylureas, DPP-4 inhibitors, SGLT-2, Alpha-glucosidase Inhibitors
, Meglitinides) And Segment Forecasts To 2020
Natural products as alpha-amylase and alpha-glucosidase inhibitors
and their hypoglycaemic potential in the treatment of diabetes: an update.
The two alpha-glucosidase inhibitors
acarbose (Precose) and miglitol (Glyset) delay the digestion of carbohydrates within the gastrointestinal tract, thereby reducing the rise in blood glucose following meals.
According to study authors, the herb seems to work similarly to oral diabetes drugs known as alpha-glucosidase inhibitors
, which impede the body's absorption of carbohydrates.