The Decipher results increased agreement in treatment recommendations between urologists and radiation oncologists, as the odds of a recommendation for adjuvant treatment
by urologists vs radiation oncologists increased from 0.
Under the terms of the agreement, SFJ will provide the funding and clinical development supervision to generate the clinical data necessary to submit axitinib for review by regulatory authorities for the adjuvant treatment
of patients at high risk of recurrent RCC following nephrectomy.
Topic areas are: epidemiology and risk factors; prevention and screening; diagnosis, staging, and prognosis; locoregional management of in situ and invasive melanoma; systemic adjuvant treatment
options; treatment of metastatic melanoma; and emerging therapeutic options for advanced melanoma.
The researchers found that patients whose tumors had low miR-26 expression had poorer survival but were more likely to respond to adjuvant treatment
with interferon alfa than patients whose tumors had high miR-26 expression.
5%) reported using antioxidants during adjuvant treatment
Irrespective of what type of surgery is involved, or the timing of the adjuvant treatment
, the use of combined treatments improves the prognosis for patients with this disease.
In January, Herceptin was approved as a single agent for adjuvant treatment
of HER2 overexpressing node-negative and node-positive breast cancer following multimodality anthracycline-based therapy.
In one-third (34 percent) of cases, surgeons did not recommend adjuvant treatment
, most often because they perceived the risks exceeded the benefits (for example, due to patient frailty or age).
They searched the literature for studies of randomised controlled trials that compared needle acupuncture given within 1 day of embryo transfer with sham acupuncture with no adjuvant treatment
The meta-analysis suggests a beneficial effect with chemotherapy in both node-negative and node-positive women, with a ten-year breast cancer mortality reduction of 6% to 8% due to adjuvant treatment
2) Adjuvant treatment
is employed when patients (1) require more than 4 surgical procedures per year, (2) manifest distal spread, or (3) experience airway distress following rapid regrowth of papillomas.
Thus, the aims of future drug development are to improve survival in the metastatic setting but also ultimately to prevent the development of metastatic disease following adjuvant treatment
The current standard-of-care for high-risk malignant melanoma is surgical treatment and no effective adjuvant treatment
currently exists, which leaves this patient category wide open for new, effective products.
Food and Drug Administration has approved Herceptin (Trastuzumab) for use in the adjuvant treatment
of HER2-positive node-positive breast cancer.
2) In the United States, seven statistical models independently developed to investigate the reduction in death rates from breast cancer 1975-2000 show that mammographical screening and adjuvant treatment
contributed almost equally.