acetylcholine

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  • noun

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a neurotransmitter that is a derivative of choline

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References in periodicals archive ?
Varenicline is a [alpha]4[beta]2 nicotinic acetylcholine receptor partial agonist which is used for the cessation of smoking (4).
Chronic intraperitoneal endotoxin treatment in rats induces resistance to d-tubocurarine, but does not produce up-regulation of acetylcholine receptors.
Functional properties of human skeletal muscle acetylcholine receptors expressed by the TE671 cell line.
It is important to understand that the nondepolarizing blocking agents also competitively block acetylcholine receptors at the autonomic ganglia, producing cardiovascular side effects on heart rate and blood pressure.
This stimulant hits acetylcholine receptors in the nervous system, leading to improved alertness.
The acetylcholine receptors are divided into muscarinic and nicotinic subtypes.
This damage occurs through mechanisms that include direct interactions with acetylcholine receptors, interference with intracellular signaling cascades, and oxidative stress.
They cover comparative genomics and drug discovery in trypanosomatids, the practical applications of comparative kinetoplastid genomics, the relevance of host-genes in malaria, nicotine acetylcholine receptors as drug and chemical targets, finding novel sodium channel inhibitors with a gene-family based approach, applications in translational medicine and using the web to identify novel drug targets.
In the brain, nicotine acts at several different types of receptors collectively known as nicotinic acetylcholine receptors (nAChRs).
California-based Targacept specialises in treatments for nervous system diseases and disorders by targeting receptors known as neuronal nicotinic acetylcholine receptors, or NNRs.
Acetylcholine travels through the neuromuscular junction and binds to acetylcholine receptors that are activated and generate a muscle contraction.
The muscarinic acetylcholine receptors (mAChR), which are members of the family of receptors that are coupled to guanine nucleotide binding proteins (G proteins) and whose structure is characterized by the seven membrane-spanning [alpha]-helical domains [2, 3], are usually solubilized in digitonin or in a mixture of digitonin and sodium cholate, which have yielded more than 50% of the soluble receptors with retention of ligand binding activity [4, 5].
13 Muscarinic Acetylcholine Receptors as Novel Targets for the Development of Therapeutics for Schizophrenia
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