Many large, randomized clinical trials have shown conclusively that both ACE inhibitors
and ARB's help lower the risk of heart attack, stroke, and worsened cardiac function.
Initial treatment with an ACE inhibitor
was about 8% more effective than was a diuretic in reducing coronary heart disease events (defined as fatal or nonfatal MI or sudden cardiac death), though the difference was not statistically significant.
Mean Annual Decline of Scores on the Modified Mini-Mental State Exam ACE inhibitor
In this study, the ARB is shown to be non-inferior to the ACE inhibitor
in preventing diabetic nephropathy.
In the present study, increasing dietary potassium intake for four weeks did not adversely affect serum potassium levels in hypertensive patients with normal renal function who were being treated with an ACE inhibitor
treatment improves all-cause mortality by 16% in patients with diabetes, including patients with and without hypertension.
Angiotensin II receptor blockers (ARBs) provide many of the same benefits of ACE inhibitors
and may be an alternative for people who cannot tolerate ACE inhibitors
For patients not suited to treatment with an ARNI, continued use of an ACE inhibitor
ACE (angiotensin-converting enzyme) inhibitors prevent the body from making ACE, which converts a naturally occurring chemical called angiotensin I into angiotensin II.
13) The ACE inhibitor
should be discontinued, and the patient should be started on a different class of antihypertensive medication.
To begin treatment for HTN in the general non-Black population (including persons with diabetes or younger than age 60), the provider should prescribe a thiazide diuretic, CCB, ACE inhibitor
, or ARB (Evidence Level B).
I freely admit that I have been following yearly urinary microalbumin in my patients with diabetes who are already on an ACE inhibitor
or an angiotensin receptor blocker (ARB).
Q I seem to cough more since my doctor prescribed an ACE inhibitor
If you have high blood pressure, chances are your doctor has prescribed either an ACE inhibitor
or a calcium channel blocker.