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  • noun

Words related to reductase

an enzyme that catalyses the biochemical reduction of some specified substance

References in periodicals archive ?
Compound Inhibitory to Rat Liver 5a-reductase from Tropical Commercial Wood Species: Resveratrol Trimmer from Melapi (Shorea sp.
Alpha blockers and the 5a-reductase inhibitors can also be given together, because some data suggest that using the drugs together is better than using either one alone.
The biologically active androgen dihydrotestosterone is produced from testosterone in the prostate by the action of type 1 and type 2 steroid 5a-reductase isoenzymes.
Dutasteride is a 5a-reductase inhibitor, already marketed in the USA under the brand name Avodart.
The ratio of 5a-THF:THF served to assess activity of the cortisol-catabolizing enzyme 5a-reductase relative to 5[beta]-reductase.
Kozarich was vice president at Merck Research Laboratories, where he was responsible for programs including antimicrobial drug discovery, enzymology, 5a-reductase biology, lipid biochemistry, nuclear receptors, ion channels and structural biology.
In other words, testosterone is a target hormone itself as well as a circulating prohormone for several target tissues that possess the converting enzymes 5a-reductase and aromatase.
PROSCAR(a) (finasteride), a synthetic 4-azasteroid compound, is a specific inhibitor of steroid 5a-reductase, an intracellular enzyme that converts testosterone into the potent androgen 5a-dihydrotestosterone (DHT).
Because of the ability of 5a-reductase inhibitors to inhibit the conversion of testosterone to DHT, finasteride may cause abnormalities of the external genitalia of a male fetus of a pregnant woman who receives finasteride.